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Osler, William, 1849-1919

"A Series of Lectures Delivered at Yale University on the Silliman Foundation in April, 1913"

Mosquitoes which had
bitten malarial patients in Italy were sent to London and there allowed
to bite Mr. Manson, son of Dr. Manson. This gentleman had not lived out
of England, where there is now no acute malaria. He had been a perfectly
healthy, strong man. In a few days following the bites of the infected
mosquitoes, he had a typical attack of malarial fever.
(3) Journal Linnaean Society, London, 1879, XIV, 304-311.
(4) Medical News, Philadelphia, 1889, LV, 689-693, and monograph
with Kilborne, Washington, 1893.
The other experiment, though of a different character, is quite as
convincing. In certain regions about Rome, in the Campania, malaria is
so prevalent that, in the autumn, almost everyone in the district is
attacked, particularly if he is a newcomer. Dr. Sambon and a friend
lived in this district from June 1 to September 1, 1900. The test was
whether they could live in this exceedingly dangerous climate for
the three months without catching malaria, if they used stringent
precautions against the bites of mosquitoes. For this purpose the hut
in which they lived was thoroughly wired, and they slept under netting.
Both of these gentlemen, at the end of the period, had escaped the
disease.


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